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Home / Primary Antibodies / IHC Antibodies

Anti-HDAC6 Antibody BHA11300339

SKU : BHA11300339

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Mfr.No.	BS1165
Alternative Names	Histone deacetylase 6 ; HD6 ; HDAC 6 ; KIAA0901 ; JM21
Categories	Primary Antibodies
Clonality	polyclonal
Description	HDAC6 is a member of the class II mammalian histone deacetylases. Human HDAC6 is composed of 1215 amino acid residues. It possesses two separate putative catalytic domains. Both catalytic domains are fully functional HDACs and contribute independently to the overall activity of HDAC6 protein. A very potent NES is present at the amino-terminus of HDAC6, which was found to play an important role in regulating the shuttling of HDAC6 protein between cytoplasm and nucleus. The shuttling process may be a critical regulatory mechanism of HDAC6 function. The expression of HDAC6 is tightly linked to the state of cell differentiation. HDAC6 may participate in coordinating expression of a group of genes involved in the remodelling of chromatin during cell differentiation.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the C-terminual of Human HDAC6.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9UBN7
Uniprot	Q9UBN7
Weight	131, 160 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: HDAC6 (H1203) polyclonal antibody detects endogenous levels of HDAC6 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC, IF

Description

WB ; IHC ; IF

Dilution

WB	1:500-1:1000
IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300339	BS1165	50µl	$190.44		Add to Cart
BHA11300339	BS1165	100µl	$294.44		Add to Cart

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