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Home / Primary Antibodies / Phospho Antibodies

Anti-HDAC1 Antibody BHA11302642

SKU : BHA11302642

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Mfr.No.	BS4693
Alternative Names	Histone deacetylase 1 ; HD1 ; RPD3L1
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	1p35.2-p35.1
Clonality	polyclonal
Description	Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (for p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated mammalian RPD3) and HDAC3, all of which are related to the yeast transcriptional regulator Rpd3p, have been identified as histone deacetylases.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human HDAC1 around the phosphorylation site of Serine 421.
Modification	phospho-S421
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q13547
Uniprot	Q13547
Weight	55 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-HDAC1 (S421) polyclonal antibody detects endogenous levels of HDAC1 protein only when phosphorylated at Ser421.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302642	BS4693	50µl	$199.33		Add to Cart
BHA11302642	BS4693	100µl	$314.89		Add to Cart

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