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Home / Primary Antibodies / IHC Antibodies

Anti-GTF2H2 Antibody BHA11301298

SKU : BHA11301298

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Mfr.No.	BS2306
Alternative Names	General transcription factor IIH subunit 2 ; Basic transcription factor 2 44 kDa subunit ; BTF2 p44 ; General transcription factor IIH polypeptide 2 ; TFIIH basal transcription factor complex p44 subunit ; GTF2H2 ; BTF2P44
Categories	Primary Antibodies
Chromosome Location	5q13.2
Clonality	polyclonal
Description	Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to the N-terminal of Human TFIIH p44.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q13888
Uniprot	Q13888
Weight	44 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: TFIIH p44 (T18) polyclonal antibody detects endogenous levels of TFIIH p44 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC, IF

Description

IHC ; IF

Dilution

IHC	1:50-1:200
IF	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301298	BS2306	50µl	$190.44		Add to Cart
BHA11301298	BS2306	100µl	$294.44		Add to Cart

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