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Home / Primary Antibodies / Phospho Antibodies

Anti-ESR2 Antibody BHA11300046

SKU : BHA11300046

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Mfr.No.	AP0318
Alternative Names	Estrogen receptor beta ; ER-beta ; Nuclear receptor subfamily 3 group A member 2 ; ESR2 ; ESTRB ; NR3A2 ; ER-β
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	14q23.2-q23.3
Clonality	polyclonal
Description	Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERa and ERb, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERa and ERb have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human ERβ around the phosphorylation site of Serine 105.
Modification	phospho-S105
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q92731
Uniprot	Q92731
Weight	48, 60 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2. Specificity: p-ERβ(S105) polyclonal antibody detects endogenous levels of ERβ protein only when phosphorylated at Ser105.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 99% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300046	AP0318	50µl	$199.33		Add to Cart
BHA11300046	AP0318	100µl	$314.89		Add to Cart

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