Rabbit polyclonal to Elastin.Elastin is a major structural protein of tissues such as aorta, which must expand rapidly and recover completely. Elastin chains are cross-linked together into an extensible 3D network. It is a molecular determinant of late arterial morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle. Elastin forms a complex with BGN and MFAP2.Defects in elastin are a cause of autosomal dominant cutis laxa. Cutis laxa is a rare connective tissue disorder characterized by loose, hyperextensible skin with decreased resilience leading to a premature aged appearance. This may be accompanied by pulmonary emphysema, bladder diverticula, pulmonary artery stenosis and pyloric stenosis. Haploinsufficiency of elastin may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS).
Formulation
Liquid
Host
Rabbit(Rb)
Guarantee
abm guarantees that all our Anti-Elastin (Several Species) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Immunogen
Elastins pooled from Pig, Human, Dog, Chicken, Rat and Cow
Quantity
1 ml
Shipping Condition
Ice Packs
Species Reactivity
Bovine ; Human ; Rat
Gene Name
Elastin (Several Species)
Clone No
Polyclonal Antibody
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Description
IHC ; WB
Reviews of Anti-Elastin (Several Species) Antibody