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Home / Antibodies

Anti-EIF5A Antibody BHA11303563

SKU : BHA11303563

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Mfr.No.	BS60424
Alternative Names	Eukaryotic translation initiation factor 5A-1 ; eIF-5A-1 ; eIF-5A1 ; Eukaryotic initiation factor 5A isoform 1 ; eIF-5A ; Rev-binding factor ; eIF-4D ; eIF4D
Categories	Primary Antibodies
Chromosome Location	17p13.1
Clonality	polyclonal
Description	In mammalian cells, translation is controlled at the level of polypeptide chain initiation by eukaryotic initiation factors. The human eukaryotic translation initiation factor 5A gene, also designated eIF-4D or eIF5A, maps to chromosome 17p13-p12 and encodes a 154 amino acid protein that is linked to cellular polyamine homeostasis. eIF5A localizes to the nuclear and cytoplasmic compartments of mammalian cells where it can stimulate ribosomal peptidyl-transferase and may be involved in nucleocytoplasmic mRNA transport and/or protein translation. eIF5A contains a unique spermidine-derived post-translational modification at Lys-50, hypusine, which is necessary for eIF5A's biochemical activity and for cellular proliferative signaling. In addition, eIF5A is a cellular cofactor for the function of the Rev transactivator protein of human immunodeficiency virus type 1 (HIV-1). Inhibition of eIF5A interaction with Rev leads to a block of the viral replication cycle.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to residues in Human EIF5A.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P63241
Uniprot	P63241
Weight	18 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: EIF5A polyclonal antibody detects endogenous levels of EIF5A protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11303563	BS60424	50µl	$190.44		Add to Cart
BHA11303563	BS60424	100µl	$294.44		Add to Cart

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