This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Host
Rabbit
Immunogen
Synthetic peptide conjugated to KLH
Isotype
IgG
Quantity
100 µl
Reactivity
Rat, Human
Recombinant
TRUE
Regulatory
RUO
Shipping Condition
Ice Packs
Antigen
DGCR8
Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Concentration
100µg/100ul
Description
Specificity: DGCR8 antibody detects endogenous levels of DGCR8 protein. Not tested with other proteins
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB, ELISA
Description
For research use onlyPeptide ELISA titer: 1:1,000-1:10,000Western blot analysis: 1:500-1000Optimal dilutions/concentrations should be determined by the end use, WB ; ELISA