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Home / Primary Antibodies / IHC Antibodies

Anti-CSF2RB Antibody BHA11300355

SKU : BHA11300355

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Mfr.No.	BS1185
Alternative Names	Cytokine receptor common subunit beta ; CDw131 ; GM-CSF/IL-3/IL-5 receptor common beta subunit ; CD131 ; CSF2RB ; IL3RB ; IL5RB ; IL3Rβ
Categories	Primary Antibodies
Chromosome Location	22q12.3
Clonality	polyclonal
Description	Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific α subunit (IL-3Rα) and a signal transducing β subunit (IL-3Rβ) common to the IL-3/IL-5/GM-CSF receptors. The α subunits are low-affinity ligand-binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the α subunits. The mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3-mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 550-600 of Human IL-3Rβ.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P32927
Uniprot	P32927
Weight	130 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: IL-3R (F587) polyclonal antibody detects endogenous levels of IL-3R protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

IHC

Description

IHC

Dilution

IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11300355	BS1185	50µl	$190.44		Add to Cart
BHA11300355	BS1185	100µl	$294.44		Add to Cart

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