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Home / Antibodies

Anti-CNTN1 Antibody BHA11304445

SKU : BHA11304445

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Mfr.No.	BS61684
Alternative Names	Contactin-1 ; Glycoprotein gp135 ; Neural cell surface protein F3 ; CNTN1
Categories	Primary Antibodies
Chromosome Location	12q12
Clonality	polyclonal
Description	Changes in synaptic efficacy can mediate crucial processes during learning and memory formation. Accumulating evidence implicates cell adhesion molecules in activity-dependent synaptic modifications associated with pairedpulse facilitation (PPF), long-term potentiation (LTP) and long-term depression (LTD). Among the cell adhesion molecules involved in these processes are the contactins. Contactins are immunoglobulin superfamily members that play a selective role in synaptic plasticity, PPF and LTD, and may regulate cell-cell interactions contributing to synaptic plasticity in conjunction with other synapse targeting molecules, including paranodin and phosphacan. In addition, contactins are essential components that control expression and distribution of Na+ channels in neurons, junctional attachment at the paranode, and ultimately the physiology of the myelinated nerve. The human Contactin 1 gene encodes a 1,018 amino acid protein. The human Contactin 3 gene encodes a 646 amino acid plasmacytoma-associated neuronal glycoprotein. The human Contactin 5 gene encodes a 1,100 amino acid neural adhesion molecule. The human Contactin 6 gene encodes a 1,028 amino acid neural adhesion molecule.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding Human CNTN1.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q12860
Uniprot	Q12860
Weight	113 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.3. Specificity: CNTN1 polyclonal antibody detects endogenous levels of CNTN1 protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:1000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11304445	BS61684	50µl	$190.44		Add to Cart
BHA11304445	BS61684	100µl	$294.44		Add to Cart

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