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Home / Primary Antibodies / IHC Antibodies

Anti-CDKL2 Antibody BHA11301168

SKU : BHA11301168

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Mfr.No.	BS2113
Alternative Names	Cyclin-dependent kinase-like 2 ; Serine/threonine-protein kinase KKIAMRE ; Protein kinase p56 KKIAMRE ; CDKL2
Categories	Primary Antibodies
Chromosome Location	4q21.1
Clonality	polyclonal
Description	The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
Host	Rabbit
Immunogen	Synthetic peptide, corresponding to amino acids 210-260 of Human KKIAMRE.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q92772
Uniprot	Q92772
Weight	56 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: KKIAMRE (L240) polyclonal antibody detects endogenous levels of KKIAMRE protein.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11301168	BS2113	50µl	$190.44		Add to Cart
BHA11301168	BS2113	100µl	$294.44		Add to Cart

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