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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD55 / Decay Accelerating Factor (DAF) Antibody BHA10200688

SKU : BHA10200688

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NeoBiotechnologies, Inc.

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Mfr.No.	1604-MSM1-P1ABX
Alternative Names	CD55 ; CD55 Cromer blood group system ; Complement decay-accelerating factor ; CROM ; DAF ; Daf-GPI ; Decay Accelerating Factor for Complement ; Decay accelerating factor GPI-form ; Decay accelerating factor soluble-form ; GPI-DAF
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	1q32
Clonality	Monoclonal
Description	Recognizes a single chain glycoprotein of 70kDa, identified as CD55 (also known as decay accelerating factor, DAF). This MAb was clustered in Kobe at the Sixth International Workshop on Human Leukocyte Differentiation Antigens as F429D-9 (N-L120). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. Anti-CD55 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).
Host	Mouse
Immunogen	Human umbilical vein endothelial cells (HUVEC)
Isotype	IgG1 Kappa
Positive Control	Jurkat, HUT-78, K562, YT, U937, MG63, and human lymphocytes. Human lymph nodes and tonsils.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P08174
Uniprot	126517
Gene Id	1604

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10200688	1604-MSM1-P1ABX	100µg	$393.20		Add to Cart

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