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Home / Primary Antibodies / Phospho Antibodies

Anti-ATP1A1 Antibody BHA11302522

SKU : BHA11302522

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Mfr.No.	BS4259
Alternative Names	Sodium/potassium-transporting ATPase subunit alpha-1 ; Short name=Na(+)/K(+) ATPase alpha-1 subunit ; Sodium pump subunit alpha-1 ; ATP1A1
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	1p13.1
Clonality	polyclonal
Description	The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP dependent transport of sodium and potassium across the cell membrane. This membrane bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium / potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families.The different isoforms of the sodium / potassium ATPase exhibit tissue specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell specific expression. The alpha subunit has been found in kidney, brain, heart, and to a lesser extent liver, skeletal and smooth muscle.
Host	Rabbit
Immunogen	Synthetic phosphopeptide derived from human Na+/K+-ATPase α1 around the phosphorylation site of Serine 16.
Modification	phospho-S16
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P05023
Uniprot	P05023
Weight	113 kDa

Description	Product: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2. Specificity: p-Na+/K+-ATPase α1 (S16) polyclonal antibody detects endogenous levels of Na+/K+-ATPase α1 protein only when phosphorylated at Ser16.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB, IHC

Description

WB ; IHC

Dilution

WB	1:500-1:1000
IHC	1:50-1:200

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11302522	BS4259	50µl	$199.33		Add to Cart
BHA11302522	BS4259	100µl	$314.89		Add to Cart

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