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Home / Antibodies

Anti-alpha-Tubulin Monoclonal Antibody (3G5)

SKU : BHA13715015

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Abbkine Scientific Co., Ltd.

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Mfr.No.	ABL1080
Alternative Names	TUBA1A; Tubulin alpha-1A chain; Alpha-tubulin 3; Tubulin B-alpha-1; Tubulin alpha-3 chain
Background	Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. TUBA1A encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that TUBA1A expression is predominantly found in morphologically differentiated neurologic cells. TUBA1A is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in TUBA1A cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Clonality	Monoclonal
Description	Featured Anti-alpha-Tubulin Monoclonal Antibody (3G5), specially designed for your immunoassay as internal control or location staining.
Formulation	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, Liquid solution
Host	Mouse
Immunogen	Recombinant Protein
Immunogen Region	Recombinant Protein
Isotype	Mouse IgG
Others	Observed Band (KD): 52
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Reactivity	Human, Mouse, Rat
Tag	TUBA1A
Note	Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:5000-1:10000), IHC-P (1:50-1:300), IF (1:200), IP (1:200).

Accession Number	Q71U36/P68363
Gene Id	7846/10376, 7846/10376

Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen, The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Storage Buffer	Liquid in PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions	Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Applications	WB, IHC-P, IF, IP

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA13715015	ABL1080	50 uL	$79		Add to Cart
BHA13715015	ABL1080	200 uL	$229		Add to Cart
BHA13715015	ABL1080	200 uLx5	$759		Add to Cart

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