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Home / Primary Antibodies / Phospho Antibodies

Anti-ALOX5 Antibody BHA11307585

SKU : BHA11307585

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Mfr.No.	BS74009
Alternative Names	5-LO ; 5LPG ; LOG5 ; 5-LOX
Categories	Primary Antibodies ; Phospho Antibodies
Chromosome Location	10q11.21
Clonality	polyclonal
Description	5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane.
Host	Rabbit
Immunogen	A phospho specific peptide corresponding to residues surrounding S271 of human ALOX5.
Modification	phospho-S271
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P09917
Uniprot	P09917
Weight	78 kDa

Description	Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Specificity: ALOX5 (phospho-S271) polyclonal antibody detects endogenous levels of ALOX5 protein only when phosphorylated at Ser271.
Purity	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Applications

WB

Description

WB

Dilution

WB	1:500-1:2000

Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA11307585	BS74009	50µl	$252.67		Add to Cart
BHA11307585	BS74009	100µl	$403.78		Add to Cart

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