Synthetic peptide derived from Human ABCB5 (910-940 amino acid region)
Isotype
IgG
Quantity
100 µl
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Shipping Condition
Ice Packs
Buffer
PBS, pH 7.4 with 0.02% sodium azide.
Concentration
100µg/100ul
Description
Specificity: This Polyclonal antibody is directed against human ABCB5 protein. The product was purified from serum by protein A chromatography. Expect reactivity with human ABCB5. Cross-reactivity with ABCB5 from other sources has not been determined.Relevance: ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.
Format
Liquid
Purity
Affinity purified
Storage
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage Condition
-20C
Applications
WB
Description
Recommended dilutionsWB: 1/1000~4000Predicted molecular weight: 90 kDa.Not yet tested in other applications.Optimal dilutions/concentrations should be determined by the end user., WB