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Home / Primary Antibodies / Monoclonal Antibodies

Angiotensinogen antibody

SKU : BHA10800390

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Mfr.No.	FNab00395
Alternative Names	AGT ; AngIAngiotensin2 ; AngIIAngiotensin3 ; AngIII ; AngiotensinI ; AngiotensinII ; AngiotensinIII ; Angiotensinogen ; ANHU ; DesAsp[1]angiotensinII ; FLJ92595
Background	Angiotensinogen is a precursor of angiotensin II(Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme(ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	monoclonal
Description	Angiotensinogen is a precursor of angiotensin II (Ang II), is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Host	Mouse
Immunogen	angiotensinogen(serpin peptidase inhibitor, clade A, member 8)
Isotype	IgG2b
Molecular Weight	53 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Secreted
Synonyms	AGT, Ang I Angiotensin 2, Ang II Angiotensin 3, Ang III, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensinogen, ANHU, Des Asp(1) angiotensin II, FLJ92595, FLJ97926, Serpin A8, SERPINA8

Uniprot	P01019
Gene Id	183
Clone No	0F2
Research Area	Cardiovascular, Metabolism
Weight	53kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:5000; IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800390	FNab00395	100ug	$260		Add to Cart

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