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Home / Primary Antibodies / Polyclonal Antibodies

Amylin antibody

SKU : BHA10800379

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Mfr.No.	FNab00384
Alternative Names	Amylin ; DAP ; Diabetesassociatedpeptide ; IAP ; IAPP ; Insulinomaamyloidpeptide ; isletamyloidpolypeptide
Background	IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic beta-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Categories	Primary Antibodies
Cellular Localization	Amyloid, Secreted
Clonality	polyclonal
Description	IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
Host	Rabbit
Immunogen	islet amyloid polypeptide
Isotype	IgG
Molecular Weight	10 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Amyloid, Secreted
Synonyms	Amylin, DAP, Diabetes associated peptide, IAP, IAPP, Insulinoma amyloid peptide, islet amyloid polypeptide

Uniprot	P10997
Gene Id	3375
Research Area	Signal Transduction
Weight	10kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC

Description

ELISA ; IHC

Dilution

IHC	1:20-1:200

Tested Application

IHC: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800379	FNab00384	100ug	$280		Add to Cart

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