The complete human amylase gene contains five intact genes: two pancreatic genes(AMY2A and AMY2B) and three salivary genes(AMYIA, AMYIB, and AMYIC). AMY2A(Pancreatic alpha-amylase)is also named as PA and is a 56 kDa protein consisting of 496 amino acids in a single polypeptide chain, folded into three domains(PMID:10657258).AMY2A and AMY2B transcripts are present in the human pancreas but not in the parotid salivary gland, while AMY1 transcripts are present in the parotid gland but not in the pancreas(PMID:1692956). This antibody can recognize both AMY1 and AMY2.
Categories
Primary Antibodies
Cellular Localization
Secreted
Clonality
monoclonal
Description
The complete human amylase gene contains five intact genes: two pancreatic genes (AMY2A and AMY2B) and three salivary genes (AMYIA, AMYIB, and AMYIC). AMY2A(Pancreatic alpha-amylase)is also named as PA and is a 56 kDa protein consisting of 496 amino acids in a single polypeptide chain, folded into three domains(PMID:10657258).AMY2A and AMY2B transcripts are present in the human pancreas but not in the parotid salivary gland, while AMY1 transcripts are present in the parotid gland but not in the pancreas(PMID:1692956). 15845-1-AP can recognize both AMY1 and AMY2.
Host
Mouse
Immunogen
amylase, alpha 2A(pancreatic)
Isotype
IgG2b
Molecular Weight
58 kDa
Reactivity
Human, Rat, Pig
Regulatory
RUO
Subcellular Location
Secreted
Synonyms
AMY2A, Amylase, alpha, Pancreatic alpha amylase
Uniprot
P04746
Clone No
1C7
Research Area
Metabolism
Weight
58kDa
Form
liquid
Format
liquid
Purification
Protein A+G purification
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)