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Home / Primary Antibodies / Polyclonal Antibodies

AMPK beta 2 antibody

SKU : BHA10800373

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Mfr.No.	FNab00378
Alternative Names	AMPKbeta2 ; AMPKsubunitbeta2 ; PRKAB2
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Categories	Primary Antibodies
Cellular Localization	Cytosol, Ucleoplasm
Clonality	polyclonal
Host	Rabbit
Immunogen	protein kinase, AMP-activated, beta 2 non-catalytic subunit
Isotype	IgG
Molecular Weight	35 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	cytosol,nucleoplasm
Synonyms	AMPK beta 2, AMPK subunit beta 2, PRKAB2

Uniprot	O43741
Gene Id	5565
Research Area	Signal Transduction, Metabolism
Weight	30kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00378.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800373	FNab00378	100ug	$240		Add to Cart

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