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Home / Primary Antibodies / Polyclonal Antibodies

AMPK beta 1 antibody

SKU : BHA10800372

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Mfr.No.	FNab00377
Alternative Names	AMPK ; AMPKbeta1 ; AMPKsubunitbeta1 ; AMPKb ; HAMPKb ; PRKAB1
Background	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.
Categories	Primary Antibodies
Cellular Localization	Cytosol, Ucleoplasm
Clonality	polyclonal
Host	Rabbit
Immunogen	protein kinase, AMP-activated, beta 1 non-catalytic subunit
Isotype	IgG
Molecular Weight	37 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	cytosol,nucleoplasm
Synonyms	AMPK, AMPK beta 1, AMPK subunit beta 1, AMPKb, HAMPKb, PRKAB1

Uniprot	Q9Y478
Gene Id	5564
Research Area	Cardiovascular, Metabolism, Signal Transduction
Weight	38kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF

Description

ELISA ; WB ; IF

Dilution

WB	1:500-1:5000
IF	1:10-1:100
IP	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00377.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800372	FNab00377	100ug	$240		Add to Cart

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