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Home / Primary Antibodies / Polyclonal Antibodies

AMOT antibody

SKU : BHA10800362

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Mfr.No.	FNab00366
Alternative Names	AMOT ; angiomotin ; KIAA1071
Background	Angiomotin belongs to the motin family of angiostatin binding protein. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Most abundant expression was found in placenta and skeletal muscle. AMOT has two isoforms with MW 130 kDa (p130) and 80 kDa (p80). This antibody recognizes p130 only.
Categories	Primary Antibodies
Cellular Localization	Cell Junction, Tight Junction
Clonality	polyclonal
Description	Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.
Host	Rabbit
Immunogen	angiomotin
Isotype	IgG
Molecular Weight	130 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell junction, Tight junction
Synonyms	AMOT, angiomotin, KIAA1071

Uniprot	Q4VCS5
Gene Id	154796
Research Area	Developmental biology, Cardiovascular
Weight	118kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB

Description

ELISA ; WB

Dilution

WB	1:200-1:2000

Tested Application

WB: 1:500-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800362	FNab00366	100ug	$240		Add to Cart

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