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Home / Primary Antibodies / Polyclonal Antibodies

Aminoacylase 1 antibody

SKU : BHA10800358

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Mfr.No.	FNab00362
Alternative Names	ACY1 ; ACY1 ; ACY1D ; ACYLASE ; Aminoacylase1
Background	This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.
Categories	Primary Antibodies
Cellular Localization	Cytoplasma
Clonality	polyclonal
Host	Rabbit
Immunogen	aminoacylase 1
Isotype	IgG
Molecular Weight	46 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasma
Synonyms	ACY 1, ACY1, ACY1D, ACYLASE, Aminoacylase 1

Uniprot	Q03154
Gene Id	95
Research Area	Cardiovascular, Metabolism
Weight	46kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:200-1:2000
IHC	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab00362.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800358	FNab00362	100ug	$240		Add to Cart

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