This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.The deduced protein sequence of the AMH monomer contains a 25 amino acid secretion specific signal peptide and a monomeric protein of 535 amino acids that, when glycosylated at two glycosylation sites, has a molecular weight of 65-70 kDa.
Categories
Primary Antibodies
Cellular Localization
Secreted
Clonality
polyclonal
Description
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin.
Host
Rabbit
Immunogen
anti-Mullerian hormone
Isotype
IgG
Molecular Weight
65-70 kD
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Secreted
Synonyms
AMH, anti Mullerian hormone, MIF, MIS
Uniprot
P03971
Gene Id
268
Research Area
Developmental biology, Immunology, Signal Transduction
Weight
59kDa,observed 66kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)