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Home / Primary Antibodies / Polyclonal Antibodies

ALPL antibody

SKU : BHA10810335

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Mfr.No.	FNab10377
Background	There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney(tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. ALPL(Alkaline phosphatase, tissue-nonspecific isozyme) is also named as AP-TNAP, TNSALP and belongs to the alkaline phosphatase family. It can exsit as a homodimer with the molecular weight of 140 kDa(PMID:18724009). ALPL was synthesized as a 66-kDa endo-b-N-acetylglucos-aminidase H(Endo H)-sensitive form, and processed to an 80-kDa mature form, which is anchored to the plasma membrane via glycosylphosphatidylinositol(GPI)(PMID:10839996).This antibody can bind the four mentioned alkaline phosphatases.
Clonality	polyclonal
Host	Rabbit
Immunogen	alkaline phosphatase, liver/bone/kidney
Immunogen Region	alkaline phosphatase, lIVer/bone/kidney
Isotype	IgG
Molecular Weight	45-60 kDa
Reactivity	Human
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:20-1:200
Subcellular Location	Cell membrane, Membrane
Synonyms	Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, Alkaline phosphatase tissue nonspecific isozyme, ALPL, BLAP, Bone Alkaline Phosphatase, NBAP

Uniprot	P05186
Gene Id	249
Research Area	Developmental biology, Cell Division and Proliferation, Stem Cells, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10377.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810335	FNab10377	100ug	$240		Add to Cart

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