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Home / Primary Antibodies / Polyclonal Antibodies

alpha Actinin antibody

SKU : BHA10809751

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Mfr.No.	FNab00322
Background	Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Clonality	polyclonal
Host	Rabbit
Immunogen	actinin, alpha 1
Immunogen Region	actinin, alpha 1
Isotype	IgG
Molecular Weight	110 kDa
Reactivity	Human, Mouse, Rat, Monkey
Recommended Dilution	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Synonyms	actinin, alpha 1, ACTN1, alpha Actinin, Alpha actinin 1, F actin cross linking protein, Non muscle alpha actinin 1

Uniprot	P12814
Gene Id	87
Research Area	Immunology, Cardiovascular

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10809751	FNab00322	100ug	$240		Add to Cart

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