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Home / Primary Antibodies / Monoclonal Antibodies

alpha 1 Antichymotrypsin / AACT antibody

SKU : BHA10800316

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Mfr.No.	FNab00318
Alternative Names	A1Antichymotrypsin ; AACT ; ACT ; Alpha1antichymotrypsin ; GIG24 ; GIG25 ; SerpinA3 ; SERPINA3
Background	Human SerpinA3, also known as Alpha 1-antichymotrypsin(AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease(COPD), Parkinson s disease(PD), Alzheimer s disease(AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.
Categories	Primary Antibodies
Cellular Localization	Secreted
Clonality	monoclonal
Description	Human SerpinA3, also known as Alpha 1-antichymotrypsin (AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson’s disease (PD), Alzheimer’s disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.
Host	Mouse
Immunogen	serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3
Isotype	IgG2b
Molecular Weight	60 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	secreted
Synonyms	A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3

Uniprot	P01011
Gene Id	12
Clone No	8F10
Research Area	Cancer, Immunology, Cardiovascular, Metabolism
Weight	48kDa,observed 65kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:1000-1:10000; IHC: 1:20-1:300

Manual	FNab00318.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800316	FNab00318	100ug	$300		Add to Cart

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