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Home / Primary Antibodies / Polyclonal Antibodies

ALDH4A1 antibody

SKU : BHA10800294

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Mfr.No.	FNab00296
Alternative Names	ALDH4 ; ALDH4A1 ; P5Cdehydrogenase ; P5CD ; P5CDh ; P5CDhL ; P5CDhS
Background	This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Categories	Primary Antibodies
Cellular Localization	Mitochondria
Clonality	polyclonal
Description	Irreversible conversion of delta-1-pyrroline-5- carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.
Host	Rabbit
Immunogen	aldehyde dehydrogenase 4 family, member A1
Isotype	IgG
Molecular Weight	61 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Mitochondrion
Synonyms	ALDH4, ALDH4A1, P5C dehydrogenase, P5CD, P5CDh, P5CDhL, P5CDhS

Uniprot	P30038
Gene Id	8659
Research Area	Metabolism
Weight	62kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab00296.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800294	FNab00296	100ug	$240		Add to Cart

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