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Home / Primary Antibodies / Polyclonal Antibodies

ALDH3A1 antibody

SKU : BHA10800290

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Mfr.No.	FNab00292
Alternative Names	Aldehydedehydrogenase3 ; ALDH3 ; ALDH3A1 ; ALDHIII
Background	Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Description	ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity).
Host	Rabbit
Immunogen	aldehyde dehydrogenase 3 family, memberA1
Isotype	IgG
Molecular Weight	55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm
Synonyms	Aldehyde dehydrogenase 3, ALDH3, ALDH3A1, ALDHIII

Uniprot	P30838
Gene Id	218
Research Area	Metabolism
Weight	50kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IF, IP

Description

ELISA ; WB ; IF ; IP

Dilution

WB	1:1000-1:10000
IF	1:10-1:100
IP	1:500-1:5000

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab00292.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800290	FNab00292	100ug	$240		Add to Cart

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