JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

ALADIN antibody

SKU : BHA10800273

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Fine Test

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	FNab00275
Alternative Names	AAA ; AAAS ; AAASb ; ADRACALA ; ADRACALIN ; ALADIN ; DKFZp586G1624 ; GL003
Background	The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.
Categories	Primary Antibodies
Cellular Localization	Nuclear Pore Complex, Nucleus
Clonality	polyclonal
Description	The AAAS gene product is the 60 kDa nuclear pore complex (NPC) protein alacrima-achalasia-adrenal insufficiency neurological disorder (ALADIN). AAAS mRNA and the ALADIN protein are ubiquitously expressed with predominance in the adrenal and central nervous system structures in human and rat. ALADIN, a Tryptophan-Aspartic acid (WD) repeat containing protein, was the first nuclear pore complex protein to be associated with hereditary neurodegenerative disease and the only nuclear pore complex protein to be associated with hereditary adrenal disease. ALADIN's precise function at the nuclear pore complex is unknown. Most naturally occurring AAAS mutations result in mislocalization of the abnormal ALADIN protein (mainly into the cytoplasm), implying that correct NPC targeting is vital for its function. (PMID: 23825130)
Host	Rabbit
Immunogen	achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
Isotype	IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Nuclear pore complex, Nucleus
Synonyms	AAA, AAAS, AAASb, ADRACALA, ADRACALIN, ALADIN, DKFZp586G1624, GL003

Uniprot	Q9NRG9
Gene Id	8086
Research Area	Neuroscience
Weight	60kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF

Description

ELISA ; WB ; IHC ; IF

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Manual	FNab00275.pdf

No Description Available.

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHA10800273	FNab00275	100ug	$240		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.