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Home / Primary Antibodies / Polyclonal Antibodies

AKNA antibody

SKU : BHA10800257

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Mfr.No.	FNab00259
Alternative Names	AKNA ; AThooktranscriptionfactor ; FLJ31001 ; FLJ33184 ; KIAA1968 ; RP1182I1.4
Background	AKNA also named as AT hook transcription factor is a 1439 amino-acids protein. AKNA, encodes a lymphoid-specific AT-hook transcription factor that is highly expressed by B and T lymphocytes. It coordinately regulates expression of the CD40 receptor and its ligand (CD154), two molecules that are critical for antigen-dependent B-cell development. AKNA expresses at least nine distinct transcripts, some of which are expressed in a tissue-specific manner. These transcripts are products of alternative splicing, alternative promoter usage, and alternative polyadenylation. The alternative AKNA transcripts are predicted to encode overlapping protein isoforms, some of which (p70 and p100) (PMID:15869410)
Categories	Primary Antibodies
Cellular Localization	Nucleus
Clonality	polyclonal
Description	Transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Binds to A/T-rich promoters.
Host	Rabbit
Immunogen	AT-hook transcription factor
Isotype	IgG
Molecular Weight	65-70 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Nucleus
Synonyms	AKNA, AT hook transcription factor, FLJ31001, FLJ33184, KIAA1968, RP11 82I1.4

Uniprot	Q7Z591
Gene Id	80709
Research Area	Metabolism
Weight	155kDa,observed 65-70kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, IHC, WB

Description

ELISA ; IHC ; WB

Dilution

WB	1:200-1:2000
IF	1:20-200

Tested Application

WB: 1:200-1:2000; IHC: 1:20-200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800257	FNab00259	100ug	$240		Add to Cart

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