Probably targets cAMP-dependent protein kinase(PKA) to the cellular membrane or cytoskeletal structures. The membrane-associated form reduces epithelial sodium channel(ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Probably targets cAMP-dependent protein kinase (PKA) to the cellular membrane or cytoskeletal structures. The membrane- associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
Host
Rabbit
Immunogen
A kinase(PRKA) anchor protein 7
Isotype
IgG
Molecular Weight
9 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cell membrane, Membrane
Synonyms
A kinase anchor protein 18 kDa, AKAP 18, AKAP 7 isoforms alpha and beta, AKAP18, AKAP7
Uniprot
Q9P0M2
Gene Id
9465
Research Area
Signal Transduction, Metabolism
Weight
9kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)