The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm
Clonality
polyclonal
Host
Rabbit
Immunogen
aryl hydrocarbon receptor interacting protein
Isotype
IgG
Molecular Weight
38 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Cytoplasm
Synonyms
AIP, ARA9, FKBP16, FKBP37, HBV X associated protein 2, Immunophilin homolog ARA9, XAP 2, XAP2
Uniprot
O00170
Gene Id
9049
Research Area
Signal Transduction, Metabolism, Neuroscience
Weight
38kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)