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Home / Primary Antibodies / Polyclonal Antibodies

AHR antibody

SKU : BHA10800229

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Mfr.No.	FNab00231
Alternative Names	Ahreceptor ; AHR ; arylhydrocarbonreceptor ; bHLHe76
Background	Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm, Nucleus
Clonality	polyclonal
Description	Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.
Host	Rabbit
Immunogen	aryl hydrocarbon receptor
Isotype	IgG
Molecular Weight	105 kDa
Reactivity	Human, Mouse
Regulatory	RUO
Subcellular Location	Cytoplasm, Nucleus
Synonyms	Ah receptor, AHR, aryl hydrocarbon receptor, bHLHe76

Uniprot	P35869
Gene Id	196
Research Area	Epigenetics, Signal Transduction, Metabolism
Weight	96kDa,observed 105kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:200-1:2000
IP	1:200-1:2000
IHC	1:20-1:200

Tested Application

WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200

Manual	FNab00231.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800229	FNab00231	100ug	$240		Add to Cart

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