Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Appears to be a negative regulator of type-1 angiotensin II receptor-mediated signaling by regulating receptor internalisation as well as mechanism of receptor desensitization such as phosphorylation. Induces also a decrease in cell proliferation and angiotensin II-stimulated transcriptional activity.
Host
Rabbit
Immunogen
angiotensin II receptor-associated protein
Isotype
IgG
Molecular Weight
18 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
membrane
Synonyms
AGTRAP, ATRAP
Uniprot
Q6RW13
Gene Id
57085
Research Area
Cardiovascular
Weight
18kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)