Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. Isoform 2: Metallocarboxypeptidase that mediates tubulin deglutamylation.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm
Clonality
polyclonal
Description
Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin. Isoform 2: Metallocarboxypeptidase that mediates tubulin deglutamylation.
Host
Rabbit
Immunogen
ATP/GTP binding protein-like 3
Isotype
IgG
Molecular Weight
73 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm
Synonyms
AGBL3, ATP/GTP binding protein like 3, CBPC3, CCP3
Antigen
AGBL3
Uniprot
Q8NEM8
Gene Id
340351
Research Area
Metabolism
Weight
116,73kDa,observed 73kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)