Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone(By similarity).
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
Host
Rabbit
Immunogen
ADAM metallopeptidase domain 19(meltrin beta)
Isotype
IgG
Molecular Weight
70 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
Membrane
Synonyms
ADAM 19, ADAM19, FKSG34, MADDAM, Meltrin beta, MLTNB
Uniprot
Q9H013
Gene Id
8728
Research Area
Developmental biology, Cardiovascular, Metabolism, Signal Transduction
Weight
105kDa,observed 70kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)