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Home / Primary Antibodies / Polyclonal Antibodies

ADAM12 antibody

SKU : BHA10800136

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Mfr.No.	FNab00137
Alternative Names	ADAM12 ; ADAM12 ; MCMP ; MCMPMltna ; Meltrinalpha ; MLTN ; MLTNA
Background	This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors (By similarity).
Host	Rabbit
Immunogen	ADAM metallopeptidase domain 12
Isotype	IgG
Molecular Weight	100 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cell membrane
Synonyms	ADAM 12, ADAM12, MCMP, MCMPMltna, Meltrin alpha, MLTN, MLTNA

Uniprot	O43184
Gene Id	8038
Research Area	Cardiovascular, Metabolism, Signal Transduction
Weight	100kDa,observed 97kDa,68kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IF, IP

Description

ELISA ; WB ; IHC ; IF ; IP

Dilution

WB	1:500-1:5000
IHC	1:20-1:200
IP	1:200-1:1000
IF	1:10-1:100

Tested Application

WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Manual	FNab00137.pdf

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800136	FNab00137	100ug	$260		Add to Cart

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