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Home / Primary Antibodies / Polyclonal Antibodies

ACVRL1 antibody

SKU : BHA10800130

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Mfr.No.	FNab00131
Alternative Names	Activinreceptorlikekinase1 ; ACVRL1 ; ACVRLK1 ; ALK1 ; ALK1 ; HHT ; HHT2 ; ORW2 ; SKR3 ; TSRI
Background	Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Categories	Primary Antibodies
Cellular Localization	Membrane
Clonality	polyclonal
Description	Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
Host	Rabbit
Immunogen	activin A receptor type II-like 1
Isotype	IgG
Molecular Weight	56 kDa
Reactivity	Human
Regulatory	RUO
Subcellular Location	Cell membrane
Synonyms	Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I

Uniprot	P37023
Gene Id	94
Research Area	Cardiovascular, Metabolism, Signal Transduction
Weight	56kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, FC, IP

Description

ELISA ; WB ; IHC ; FC ; IP

Dilution

WB	1:200-1:1000
IHC	1:100-1:400
IP	1:200-1:1000

Tested Application

WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800130	FNab00131	100ug	$240		Add to Cart

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