Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor(NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
Categories
Primary Antibodies
Cellular Localization
Cytoplasm, cytoskeleton
Clonality
polyclonal
Description
Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors.
Host
Rabbit
Immunogen
ARP3 actin-related protein 3 homolog B(yeast)
Isotype
IgG
Molecular Weight
48 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Cytoplasm, Cytoskeleton
Synonyms
ACTR3B, Actin like protein 3B, ARP3 beta, ARP4, ARP11
Uniprot
Q9P1U1
Gene Id
57180
Research Area
Cell Division and Proliferation
Weight
48kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)