Acyl-CoA synthetases(ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage(By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids(By similarity). It was suggested that it may also stimulate fatty acid oxidation(By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Acyl-CoA synthetases (ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage (By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids (By similarity). It was suggested that it may also stimulate fatty acid oxidation (By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
Host
Rabbit
Immunogen
acyl-CoA synthetase long-chain family member 5
Isotype
IgG
Molecular Weight
70 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
membrane
Synonyms
ACS2, ACS5, ACSL5, FACL5, LACS 5
Uniprot
Q9ULC5
Gene Id
51703
Research Area
Metabolism
Weight
76kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)