Acyl-CoA synthetases(ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis(By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates(By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL(very low density lipoproteins).
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins).
Host
Rabbit
Immunogen
acyl-CoA synthetase long-chain family member 3
Isotype
IgG
Molecular Weight
80 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
membrane
Synonyms
ACSL3, LACS3, ACS3, FACL3, LACS 3
Antigen
ACSL3
Uniprot
O95573
Gene Id
2181
Research Area
Metabolism
Weight
80kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)