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Home / Primary Antibodies / Polyclonal Antibodies

Aconitase 2 antibody

SKU : BHA10800087

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Mfr.No.	FNab00088
Alternative Names	GenesymbolACO2SynonymsACO2 ; Aconitase ; aconitase2 ; aconitase2 ; mitochondrial ; ACONM ; Citratehydrolyase
Background	ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration(ICRD).
Categories	Primary Antibodies
Cellular Localization	Mitochondria
Clonality	polyclonal
Description	ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration (ICRD).
Host	Rabbit
Immunogen	aconitase 2, mitochondrial
Isotype	IgG
Molecular Weight	85 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Mitochondrion
Synonyms	Gene symbol ACO2 Synonyms ACO2, Aconitase, aconitase 2, aconitase 2, mitochondrial, ACONM, Citrate hydro lyase

Uniprot	Q99798
Gene Id	50
Research Area	Metabolism
Weight	85kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:500-1:5000
IHC	1:20-1:200

Tested Application

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:50-1:200

Manual	FNab00088.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800087	FNab00088	100ug	$240		Add to Cart

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