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Home / Primary Antibodies / Polyclonal Antibodies

ACC1 antibody

SKU : BHA10800076

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Mfr.No.	FNab00077
Alternative Names	ACACASynonymsACAC ; ACACA ; ACC ; ACC1 ; ACCA ; AcetylCoAcarboxylase1
Background	ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
Categories	Primary Antibodies
Cellular Localization	Cytoplasm
Clonality	polyclonal
Description	ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase (FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.
Host	Rabbit
Immunogen	acetyl-Coenzyme A carboxylase alpha
Isotype	IgG
Molecular Weight	270 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	Cytoplasm
Synonyms	ACACA Synonyms ACAC, ACACA, ACC, ACC1, ACCA, Acetyl CoA carboxylase 1

Uniprot	Q13085
Gene Id	31
Research Area	Cardiovascular, Metabolism
Weight	270kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP, IF

Description

ELISA ; WB ; IHC ; IP ; IF

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IF	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab00077.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800076	FNab00077	100ug	$240		Add to Cart

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