GTPase-activating protein(GAP) for ADP ribosylation factor 6(ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Categories
Primary Antibodies
Cellular Localization
Endosome, Membrane
Clonality
polyclonal
Description
GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.
Host
Rabbit
Immunogen
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Isotype
IgG
Molecular Weight
82 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
Endosome, Membrane
Synonyms
ACAP1, Centaurin beta 1, CENTB1, Cnt b1, KIAA0050
Uniprot
Q15027
Gene Id
9744
Research Area
Signal Transduction, Metabolism
Weight
82kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)