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Home / Primary Antibodies / Polyclonal Antibodies

ACADVL antibody

SKU : BHA10800067

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Mfr.No.	FNab00068
Alternative Names	ACAD6 ; ACADVL ; LCACD ; VLCAD
Background	Very long-chain acyl-CoA dehydrogenase (VLCAD) is one of four flavoproteins which catalyze the initial step of the mitochondrial b-oxidation spiral. It belongs to the acyl-CoA dehydrogenase family and is a homodimer of a 71-kDa polypeptide. The molecular mass of the nondenatured trypsinized VLCAD is 98 kDa, by gel filtration chromatography, indicating that it is a homodimer of the 48 kDa(tryptic digest) polypeptide(PMID:9461620). Defects in ACADVL are the cause of acyl-CoA dehydrogenase very long chain deficiency (ACADVLD). It has 2 isoforms(70 kDa and 68 kDa ) produced by alternative splicing and a transit peptide.
Categories	Primary Antibodies
Cellular Localization	Mitochondria
Clonality	polyclonal
Description	Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.
Host	Rabbit
Immunogen	acyl-Coenzyme A dehydrogenase, very long chain
Isotype	IgG
Molecular Weight	48 kDa,68-73 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Subcellular Location	mitochondrion
Synonyms	ACAD6, ACADVL, LCACD, VLCAD

Uniprot	P49748
Gene Id	37
Research Area	Metabolism
Weight	70kDa,observed 98kDa and 51kDa

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC, IP

Description

ELISA ; WB ; IHC ; IP

Dilution

WB	1:200-1:2000
IHC	1:20-1:200
IP	1:200-1:2000

Tested Application

WB: 1:200-1:2000; IHC: 1:20-1:200

Manual	FNab00068.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800067	FNab00068	100ug	$240		Add to Cart

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