This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.
Categories
Primary Antibodies
Cellular Localization
Mitochondria
Clonality
polyclonal
Description
Introduces a double bond at position 2 in saturated acyl-CoA's of short chain length, i.e. less than 6 carbon atoms.
Host
Rabbit
Immunogen
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain
Isotype
IgG
Molecular Weight
44 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Subcellular Location
mitochondrion
Synonyms
ACAD3, ACADS, Butyryl CoA dehydrogenase, SCAD
Uniprot
P16219
Gene Id
35
Research Area
Cardiovascular, Metabolism
Weight
44kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)