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Home / Primary Antibodies / Polyclonal Antibodies

ABCC6 antibody

SKU : BHA10810303

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Mfr.No.	FNab10348
Background	The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).
Clonality	polyclonal
Host	Rabbit
Immunogen	ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Immunogen Region	ATP-binding cassette, sub-family C (CFTR/MRP), member 6
Isotype	IgG
Molecular Weight	165 kDa
Reactivity	Human
Recommended Dilution	IHC: 1:20-1:200
Synonyms	ABC34, ABCC6, ARA, EST349056, MLP1, MOAT E, MOATE, MRP6, PXE, PXE1

Uniprot	O95255

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	IHC: 1:20-1:200

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10348.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810303	FNab10348	100ug	$240		Add to Cart

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