Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
Categories
Primary Antibodies
Cellular Localization
Membrane
Clonality
polyclonal
Description
Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
Host
Rabbit
Immunogen
ATP-binding cassette, sub-family A(ABC1), member 7
Isotype
IgG
Molecular Weight
234 kDa
Reactivity
Human, Mouse
Regulatory
RUO
Subcellular Location
membrane
Synonyms
ABCA7 Synonyms ABCA SSN, ABCA7, ABCX, Autoantigen SS N, FLJ40025, Macrophage ABC transporter
Uniprot
Q8IZY2
Gene Id
10347
Research Area
Metabolism, Neuroscience
Weight
234kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)