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Home / Primary Antibodies / Monoclonal Antibodies

4EBP1 antibody

SKU : BHA10800006

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Mfr.No.	FNab00006
Alternative Names	4EBP1 ; 4EBP1 ; BP1 ; eIF4Ebindingprotein1 ; EIF4EBP1 ; PHASI
Background	Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Categories	Primary Antibodies
Clonality	monoclonal
Description	Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Host	Mouse
Immunogen	eukaryotic translation initiation factor 4E binding protein 1
Isotype	IgG2b
Molecular Weight	12 kDa
Reactivity	Human
Regulatory	RUO
Synonyms	4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I

Uniprot	Q13541
Gene Id	1978
Clone No	6C4
Research Area	Cancer, Metabolism
Weight	12kDa

Form	liquid
Format	liquid
Purification	Protein A+G purification
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications

ELISA, WB, IHC

Description

ELISA ; WB ; IHC

Dilution

WB	1:1000-1:10000
IHC	1:20-1:200
IF	1:20-1:200

Tested Application

WB: 1:500-1:2000; IF: 1:20-1:200

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SKU	Supplier No.	Size	Your price	Quantity
BHA10800006	FNab00006	100ug	$280		Add to Cart

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