In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating(ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes(ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms.(PMID:24373925). ALOX15B has 4 isoforms produced by alteative splicing with the MW of 76, 67, 69 and 73 kDa.
Categories
Primary Antibodies
Clonality
polyclonal
Description
In humans, there are 6 functional lipoxygenases genes. Two of them encode for arachidonic acid 12-lipoxygenating (ALOX12, ALOX12B) and two for 15-lipoxygenating enzymes (ALOX15, ALOX15B). ALOX15B has been described as the most abundant 15-lipoxygenating enzyme species in human carotid atherosclerotic lesions and to be associated with cerebrovascular symptoms. (PMID:24373925). ALOX15B has 4?isoforms?produced by?alteative splicing with the MW of 76, 67, 69 and 73 kDa. 13073-1-AP can also recognize the mouse Alox8 protein.
Host
Rabbit
Immunogen
arachidonate 15-lipoxygenase, type B
Isotype
IgG
Molecular Weight
76 kDa
Reactivity
Human, Mouse, Rat
Regulatory
RUO
Synonyms
ALOX15B;Arachidonate 15-lipoxygenase B,15-LOX-B,15-LOX-2,Arachidonate 15-lipoxygenase type II,Linoleate 13-lipoxygenase 15-Lob
Antigen
15 Lipoxygenase 2
Uniprot
O15296
Research Area
Metabolism
Weight
76kDa
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)